TruNode is a sterile, wireless, single-use gamma probe optimized for the most common radio-guided surgical procedures. The probe senses hotspots better than existing probes due to its innovative detector and heuristic audio feedback technology. It is simple to use, with finger-tip pushbutton switches. The switches give the surgeon complete control from the sterile field, including switching between high-sensitivity ‘scan’ and high-resolution ‘point’ modes. Voice reporting and statistical algorithms take the guesswork out of count-rate determination. Sterility relieves nursing staff of infection controls. An IV pole mountable User Feedback Unit provides audible and visual user feedback.